Recombinant Mouse Transforming Growth Factor-beta Receptor Type II is produced by our Mammalian expression system and the target gene encoding Ile24-Asp159 is expressed with a 6His tag at the C-terminus. (Previous Cat# CM05)

Recombinant Mouse TGF-beta RII/TGFBR2 (C-His)

Name: Recombinant Mouse TGF-beta RII/TGFBR2 (C-His)
SKU: BP192-10ug

SKU: BP192-10ug

$79.00

Quantity

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Email: orders@bonopusbio.com

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

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Endotoxin

less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

Q62312-2

Species

Mouse

Expression System

Human 293 Cells

Target Sequence

Ile24-Asp159

C-6His

Formulation

Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4

Packaging

Ambient

Background

Transforming growth factor-beta receptor type II (TGF-β RII) contains a C-terminal protein kinase domain and an N-terminal ectodomain and is the member of the transforming growth factor-beta (TGF-β) receptor subfamily. TGF-β RII is capable of binding TGF-beta 1, TGF-beta 3, and TGF-beta 5 with sufficient affinity to act as an inhibitor of these isoforms at high concentrations. TGF-β RII has a protein kinase domain that forms a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein can enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.

Purity

greater than 95% as determined by reducing SDS-PAGE.

TGF-beta receptor type-2; TGFR-2; TGF-beta type II receptor; Transforming growth factor-betareceptor type II; TGF-beta receptor type II; TbetaR-II; Tgfbr2