Recombinant Mouse IL-18 binding protein d is produced by our Mammalian expression system and the target gene encoding Thr29-Ala193 is expressed with a Fc tag at the C-terminus.

Recombinant Mouse Interleukin-18 Binding Protein Isoform d/IL-18 BPd (C-Fc)

Name: Recombinant Mouse Interleukin-18 Binding Protein Isoform d/IL-18 BPd (C-Fc)
SKU: CM45-10ug

SKU: CM45-10ug

$68.00

Quantity

[{"key":"CM45-1mg","value":"Backorder"},{"key":"CM45-500ug","value":"Backorder"},{"key":"CM45-50ug","value":"In Stock"},{"key":"CM45-10ug","value":"Backorder"}]

FAQ

Contact Us

Phone: 800-943-6396 ext#1

Email: orders@bonopusbio.com

Distributors

Have Other Questions?

Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

Datasheet not available? Submit a request here

Endotoxin

Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

Q9Z0M9

Species

Mouse

Expression System

Human Cells

Target Sequence

Thr29-Ala193

C-Fc

Formulation

Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.

Packaging

Ambient

Background

Interleukin 18 binding protein (IL-18BP) is a physiological inhibitor that acts through binding to the receptor-binding site of IL-18. IL-18 stimulates INF-γ, which then stimulates 18BP production via NF-κB. The interaction between IL-18 and IL-18BP has a significant role in the inflammation process. IL-18 BPs have four isoforms, a, b, c and d, which are spliced by different ways. The IL-18 BP isoforms a and c each contain one immunoglobulin (Ig)-like C2-type domain which is essential to the binding and neutralizing properties of the binding proteins. The IL-18 BP isoforms b and d lack a complete Ig domain. The expression of IL-18 and the IL-18BP are indentified in immune tissues such as the spleen, but also in nonimmune cells including keratinocytes.