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Recombinant Human Myelin-Associated Glycoprotein/MAG/Siglec-4a (C-6His)
Recombinant Human Myelin Associated Glycoprotein is produced by our Mammalian expression system and the target gene encoding Gly20-Pro516 is expressed with a 6His tag at the C-terminus.

Recombinant Human Myelin-Associated Glycoprotein/MAG/Siglec-4a (C-6His)

SKU: C897-10ug
$110.00Price
In Stock
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Accession Number
P20916
Species
Human
Expression System
Human Cells
Target Sequence
Gly20-Pro516
Tag
C-His
Formulation
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Packaging
Ambient
Background
Human Myelin-Associated Glycoprotein,also known as MAG, Siglec-4,is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins.MAG contains 4 Ig-like C2-type domains and 1 Ig-like V-type domain.MAG functions as an adhesion molecule during neural development. MAG is believed to be involved in myelination during nerve regeneration. it is a adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells and Preferentially binds to alpha-2,3-linked sialic acid. Soluble MAG, which is released from myelin in large quantities, has been identified in normal human tissues and in tissues from patients with neurological disorders. It is believed that this soluble MAG might contribute to the lack of CNS neuron regeneration after injury.
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Myelin-Associated Glycoprotein; Siglec-4a; MAG; GMA
Alternative Names
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Citation
NA
Activity
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