Recombinant Human IgG Fc fragment receptor transporter is produced by our Mammalian expression system and the target gene encoding Ala24-Ser297&Ile21-Met119 is expressed with a 6His tag at the C-terminus.

Recombinant Human FcRn & B2M Heterodimer

Name: Recombinant Human FcRn & B2M Heterodimer
SKU: BP223-10ug

SKU: BP223-10ug

$110.00

Quantity

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$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

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Certificate of Analysis

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Endotoxin

less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.

Accession Number

P55899&P61769

Species

Human

Expression System

Human Cells

Target Sequence

Ala24-Ser297&Ile21-Met119

C-6His

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, 0.05%Tween 80, pH7.4

Packaging

Ambient

Background

FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51（alpha chain) and Beta-2-microglobulin p14（Beta chain). The complex is formed noncovalently and has similar structure to MHC class I-like heterodimer. FcRn binds to the Fc region of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk. FcRn complex may involve in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin plays a role in the presentation of peptide antigens to the immune system.