Recombinant Human LBP is produced by our Mammalian expression system and the target gene encoding Ala26-Val481 is expressed with a 6His tag at the C-terminus. Bon Opus Cat. #C370

Recombinant Human Lipopolysaccharide-Binding Protein/LBP (C-6His)

Name: Recombinant Human Lipopolysaccharide-Binding Protein/LBP (C-6His)
SKU: C370-10ug

SKU: C370-10ug

$123.00

Quantity

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Shipping Information

$48 Standard Overnight flat rate for products shipped in room temperature within the United States.

Additional $27 Ice Packs shipment fee is required for liquid proteins.

Please contact us to order for international shipments.

Certificate of Analysis

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Endotoxin

Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

Accession Number

P18428

Species

Human

Expression System

Human Cells

Target Sequence

Ala26-Val481

C-His

Formulation

Lyophilized from a 0.2 um filtered solution of 20mM Tris-HCl,500mM NaCl,1mM EDTA,pH 8.0.

Packaging

Ambient

Background

Lipopolysaccharide binding protein (LBP) is a plasma protein, belongs to a member of structurally and functionally related proteins which includes bactericidal permeability-increasing protein (BPI), plasma cholesteryl ester transfer protein (CETP) and phospholipid transfer protein (PLTP). It is involved in the acute-phase immunologic response to gram-negative bacterial infections. In cooperation with BPI. LBP binds LPS and interacts with the CD14 receptor, most likely playing a role in regulating LPS-dependent monocyte responses. Studies suggest that LBP is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. Finally, t The LBP gene is found on chromosome 20, directly downstream of the BPI gene.